MpiGt(OST90588)Lex
Gene trapped Allele Detail
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Symbol: |
MpiGt(OST90588)Lex |
Name: |
mannose phosphate isomerase; gene trap OST90588, Lexicon Genetics |
MGI ID: |
MGI:3628756 |
Synonyms: |
Mpi-, MpiGt(VICTR48)1Lex |
Gene: |
Mpi Location: Chr9:57451539-57460046 bp, - strand Genetic Position: Chr9, 31.05 cM, cytoband C
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Alliance: |
MpiGt(OST90588)Lex page
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Mutant Cell Line: |
OST90588 |
Germline Transmission: |
Earliest citation of germline transmission:
J:109220
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Parent Cell Line: |
Lex-1 (ES Cell)
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Strain of Origin: |
129S5/SvEvBrd
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Project Collection: |
Lexicon
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Allele Type: |
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Gene trapped (Null/knockout, Reporter) |
Mutation: |
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Insertion of gene trap vector
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Mutation details: The insertion of the VICTR48 vector into intron 1 resulted in the splicing of 5' exonic sequences to a neomycin resistance cassette. The vector contained long terminal repeats, neo-pA, BTK and additional LTR sequence. The final product was a fusion of exon 1 and the neo. Protein expression was not detected in mutant embryos.
(J:109220)
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Sequence Tags: |
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Sequence tag details (1 tag)
Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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Genome Context: |
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Genome Browser view of this mutation
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mpi Mutation: |
31 strains or lines available
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Original: |
J:109220 DeRossi C, et al., Ablation of mouse phosphomannose isomerase (Mpi) causes mannose 6-phosphate accumulation, toxicity, and embryonic lethality. J Biol Chem. 2006 Mar 3;281(9):5916-27 |
All: |
2 reference(s) |
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