Raf1^tm2.1Bacc
Targeted Allele Detail

Summary

• Symbol: Raf1^tm2.1Bacc
• Name: v-raf-leukemia viral oncogene 1; targeted mutation 2.1, Manuela Baccarini
• MGI ID: MGI:3622475
• Synonyms: c-raf-1^delta
• Gene: Raf1 Location: Chr6:115595530-115653596 bp, - strand Genetic Position: Chr6, 53.62 cM, cytoband C3
• Alliance: Raf1^tm2.1Bacc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:105998
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele was produced by crossing mice carrying the original conditional targeted mutation (J:93687) to Meox2^tm1(cre)Sor mice to produce mice heterozygous for the deleted allele and Meox2^tm1(cre)Sor. (J:105998)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Raf1 Mutation: 114 strains or lines available

References

• Original: J:105998 Galabova-Kovacs G, et al., Essential role of B-Raf in ERK activation during extraembryonic development. Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1325-30
• All: 1 reference(s)