Slc6a9^tm1.1Bois
Targeted Allele Detail

Summary

• Symbol: Slc6a9^tm1.1Bois
• Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 9; targeted mutation 1.1, Detlev Boison
• MGI ID: MGI:3622080
• Synonyms: Glyt1tm1.2fl
• Gene: Slc6a9 Location: Chr4:117692240-117726502 bp, + strand Genetic Position: Chr4, 53.62 cM
• Alliance: Slc6a9^tm1.1Bois page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:106967
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: ES cells carrying a floxed sequence encompassing exons 5-11 and an frt-flanked neomycin resistance cassett in intron 11 were electroporated with FLP recombinase to remove the neo cassette. (J:106967)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc6a9 Mutation: 28 strains or lines available

References

• Original: J:106967 Yee BK, et al., Disruption of glycine transporter 1 restricted to forebrain neurons is associated with a procognitive and antipsychotic phenotypic profile. J Neurosci. 2006 Mar 22;26(12):3169-81
• All: 7 reference(s)