Tsz1^C57BL/6J
QTL Variant Detail

Summary

• QTL variant: Tsz1^C57BL/6J
• Name: thymus size 1; C57BL/6J
• MGI ID: MGI:3615629
• QTL: Tsz1 Location: unknown Genetic Position: Chr5, Syntenic

Variant origin

• Strain of Specimen: C57BL/6J

Variant description

• Allele Type: QTL

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:7417

Tsz1, a QTL affecting adult thymus size was mapped using 20 BXD (B=C57BL/6J; D=DBA/2J) and 24 AXB/BXA (B=C57BL/6J; A=A/J) recombinant inbred strains. Parental strain C57BL/6J exhibits a 2-fold increase in thymus size compared to parental strains DBA/2J and A/J. The strain distribution pattern of Tsz1 in BXD RI strains showed statistically significant correlation to Spp1 (56 cM) on mouse Chromosome 5. The genetic distance between Tsz1 and Spp1 is estimated to be approximately 8 cM. However, Tsz1 did not show linkage to Gusb (72 cM), the chromosome 5 marker in the AXB/BXA RI strains.

References

• Original: J:7417 Peleg L, et al., Genetic control of thymus size in inbred mice. J Hered. 1984 Mar-Apr;75(2):126-30
• All: 1 reference(s)