Hye^C3H/Di
QTL Variant Detail

Summary

• QTL variant: Hye^C3H/Di
• Name: Hya expression; C3H/Di
• MGI ID: MGI:3615627
• QTL: Hye Location: unknown Genetic Position: Chr17, Syntenic

Variant origin

• Strain of Specimen: C3H/Di

Variant description

• Allele Type: QTL

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:6255

A locus named Hye (Hya expression) on mouse Chromosome 17 affects expression of the male-specific H-Y antigen. Analysis of (B10.T-H2^y2/(6R) x C3H/Di)F1 hybrids outcrossed to B10.A(5R) or B10.D2 animals showed that the Hye locus is more closely linked to the t complex (4.02 cM) than the H2 complex (23 cM). Parental strains B10.T-H2^y2/(6R) and B10.A(5R) exhibit high H-Y expression whereas parental strains C3H/Di and B10.D2 exhibit low H-Y expression.

References

• Original: J:6255 Kralova J, et al., H-Y antigen: genetic control of the expression as detected by host-versus-graft popliteal lymph node enlargement assay maps between the T and H-2 complexes. J Immunogenet. 1979 Dec;6(6):429-38
• All: 1 reference(s)