Ube2i^tm1Adej
Targeted Allele Detail

Summary

• Symbol: Ube2i^tm1Adej
• Name: ubiquitin-conjugating enzyme E2I; targeted mutation 1, Anne Dejean
• MGI ID: MGI:3614393
• Synonyms: Ubc9^fl, Ubc9^t
• Gene: Ube2i Location: Chr17:25479482-25493856 bp, - strand Genetic Position: Chr17, 12.53 cM
• Alliance: Ube2i^tm1Adej page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104945
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted to flank exons 2 and 3 in opposite orientation such that expression of cre-recombinase would result the inversion of the sequence. (J:104945)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ube2i Mutation: 22 strains or lines available

References

• Original: J:104945 Nacerddine K, et al., The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice. Dev Cell. 2005 Dec;9(6):769-79
• All: 6 reference(s)