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Rvil1CE/J
QTL Variant Detail
Summary
QTL variant: Rvil1CE/J
Name: radiation induced leukemia virus susceptibility; CE/J
MGI ID: MGI:3611360
QTL: Rvil1  Location: unknown  Genetic Position: Chr2, Syntenic
Variant
origin
Strain of Specimen:  CE/J
Variant
description
Allele Type:    QTL
Mutation:    Undefined
    This allele confers susceptibility to radiation induced leukemia virus compared to C57BL/10J. (J:7027)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:7027

Susceptibility to radiation induced leukemia is determined by locus Rvil1. The assignment of this locus to Chromosome 2, between H-3 and a, was made by the analysis of susceptible congenic B10.CE-H3bb/(30NX)SnDcr mice in which the locus Rvil1 was cotransferred from CE/J to the C57BL10/J background. An association of Chromosome 2 gene Ly-11 with Rvil-1 was also observed from progeny involving F2 crosses between A/J and C57BL/6J mice.

References
Original:  J:7027 Meruelo D, et al., Induction of leukemia by both fractionated x-irradiation and radiation leukemia virus involves loci in the chromosome 2 segment H-30-A. Proc Natl Acad Sci U S A. 1983 Jan;80(2):462-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/24/2023
MGI 6.22
The Jackson Laboratory