Testm1Cro
Targeted Allele Detail
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Symbol: |
Testm1Cro |
Name: |
testin LIM domain protein; targeted mutation 1, Carlo M Croce |
MGI ID: |
MGI:3587810 |
Synonyms: |
TES- |
Gene: |
Tes Location: Chr6:17065148-17105824 bp, + strand Genetic Position: Chr6, 7.67 cM
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Alliance: |
Testm1Cro page
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Histopathology and cell proliferation in forestomach of Testm1Cro/Tes+ and Testm1Cro/Testm1Cro mice on a zinc deficient diet
Show the 2 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:100181
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Parent Cell Line: |
RW-4 (ES Cell)
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Strain of Origin: |
129X1/SvJ
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Allele Type: |
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Targeted (Null/knockout) |
Mutation: |
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Insertion
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Mutation details: A neomycin resistance cassette was inserted into exon 3. Mutants produced two aberrant transcripts in which the first half of exon 3 was deleted. Western blot revealed that these transcripts were not translated into protein.
(J:100181)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Tes Mutation: |
30 strains or lines available
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Original: |
J:100181 Drusco A, et al., Knockout mice reveal a tumor suppressor function for Testin. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):10947-51 |
All: |
2 reference(s) |
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