Hdac1^MommeD5
Chemically induced Allele Detail

Summary

• Symbol: Hdac1^MommeD5
• Name: histone deacetylase 1; modifiers of murine metastable epiallele D5
• MGI ID: MGI:3586552
• Gene: Hdac1 Location: Chr4:129409897-129436506 bp, - strand Genetic Position: Chr4, 63.26 cM
• Alliance: Hdac1^MommeD5 page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Intragenic deletion
• Mutation details: A 7 bp deletion occurs in this ENU mutant in exon 13. This results in a frame shift that changes the last 12 amino acid residues and adds an additional 25 amino acids. The C-terminal sumoylated Lysine at position 476 is lost. (J:142335)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hdac1 Mutation: 36 strains or lines available

References

• Original: J:99816 Blewitt ME, et al., An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse. Proc Natl Acad Sci U S A. 2005 May 24;102(21):7629-34
• All: 3 reference(s)