Krt12^tm2(rtTA)Wwk
Targeted Allele Detail

Summary

• Symbol: Krt12^tm2(rtTA)Wwk
• Name: keratin 12; targeted mutation 2, Winston W Y Kao
• MGI ID: MGI:3583535
• Synonyms: Krt12-rtTa, Krt12^rtTa
• Gene: Krt12 Location: Chr11:99306492-99313085 bp, - strand Genetic Position: Chr11, 62.92 cM
• Alliance: Krt12^tm2(rtTA)Wwk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99414
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Transactivator)
• Mutation: Insertion
• Mutation details: An internal ribosomal entry site-reverse tetracycline transcription activator gene was inserted in frame in exon 8, 3' to the stop codon. Expression was confirmed by Western blot analysis of eye tissues. (J:99414)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Krt12 Mutation: 22 strains or lines available

References

• Original: J:99414 Chikama T, et al., Characterization of tetracycline-inducible bitransgenic Krt12rtTA/+/tet-O-LacZ mice. Invest Ophthalmol Vis Sci. 2005 Jun;46(6):1966-72
• All: 14 reference(s)