Lmx1b^tm1Imc
Targeted Allele Detail

Summary

• Symbol: Lmx1b^tm1Imc
• Name: LIM homeobox transcription factor 1 beta; targeted mutation 1, Iain McIntosh
• MGI ID: MGI:3582157
• Synonyms: lmx1b^3'LacZ
• Gene: Lmx1b Location: Chr2:33450977-33530620 bp, - strand Genetic Position: Chr2, 22.48 cM
• Alliance: Lmx1b^tm1Imc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:95961
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An NLS-IRES-lacZ-loxP-neo-loxP cassette was inserted the 3' UTR. The neo was subsequentely removed by crossing with mice expressing Cre recombinase in the germline. (J:95961)

Expression

In Mice Carrying this Mutation:

44 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lmx1b Mutation: 16 strains or lines available

References

• Original: J:95961 Dunston JA, et al., A neurological phenotype in nail patella syndrome (NPS) patients illuminated by studies of murine Lmx1b expression. Eur J Hum Genet. 2005 Mar;13(3):330-5
• All: 1 reference(s)