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Mesp2tm6Ysa
Targeted Allele Detail
Summary
Symbol: Mesp2tm6Ysa
Name: mesoderm posterior 2; targeted mutation 6, Yumiko Saga
MGI ID: MGI:3580268
Gene: Mesp2  Location: Chr7:79460475-79463179 bp, + strand  Genetic Position: Chr7, 45.18 cM
Alliance: Mesp2tm6Ysa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:98581
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA modified version of YFP, venus, as well as a floxed PGK-neo selection cassette, replaced two exons. Confocal microscopy of live embryos demonstrated localization of the Mesp2 knock-in expression. (J:98581)
Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mesp2 Mutation:  30 strains or lines available
References
Original:  J:98581 Morimoto M, et al., The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity. Nature. 2005 May 19;435(7040):354-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory