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Allele Detail
Symbol: Krasb
Name: Kirsten rat sarcoma viral oncogene homolog; b variant
MGI ID: MGI:3579273
Synonyms: 0.70-kB KRAS2 allele, Allele 2, resistant allele
Gene: Kras  Location: Chr6:145162425-145195965 bp, - strand  Genetic Position: Chr6, 77.37 cM, cytoband G2
Alliance: Krasb page
Strain of Origin:  Not Applicable
Allele Type:    Not Applicable
Mutation:    Undefined
    This variant results in an EcoRI band of 0.7 kb.
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structure(s)
Tumor Data
List all tumor models in MMHCdb carrying Krasb
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kras Mutation:  76 strains or lines available
The b variant has been observed in the following strains: AKR/J, B10.O20, C58/J, C57BL/6J, C57L/J, C3H/HeJ, OcB6, OcB15 SJL/J and DBA/2J. This variant has been shown to confer resistance to pulmonary tumors.
Original:  J:8509 Ryan J, et al., An EcoRI restriction fragment length polymorphism at the KRAS2 locus on mouse chromosome 6. Nucleic Acids Res. 1986 Nov 25;14(22):9222
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.24
The Jackson Laboratory