Slc19a1^tm1Rsc
Targeted Allele Detail

Summary

• Symbol: Slc19a1^tm1Rsc
• Name: solute carrier family 19 (folate transporter), member 1; targeted mutation 1, Robert S Chapkin
• MGI ID: MGI:3573752
• Synonyms: RFC1^-
• Gene: Slc19a1 Location: Chr10:76868103-76886266 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Slc19a1^tm1Rsc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:96380
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 3 and 4 were removed via cre-mediated excision. (J:96380)

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc19a1 Mutation: 30 strains or lines available

References

• Original: J:96380 Ma DW, et al., Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis. Cancer Res. 2005 Feb 1;65(3):887-97
• All: 4 reference(s)