Tg(Fabp1-OLIG2)#Flds
Transgene Detail

Summary

• Symbol: Tg(Fabp1-OLIG2)#Flds
• Name: transgene insertion #, Alan P Fields
• MGI ID: MGI:3531329
• Synonyms: PKC betaII
• Transgene: Tg(Fabp1-OLIG2)#Flds Location: unknown
• Alliance: Tg(Fabp1-OLIG2)#Flds page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Fabp1-OLIG2)#Flds expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  OLIG2 (10215)

  Olig2

  (MGI:1355331)

• Mutation details: A cDNA fragment encoding a full length human PKC BetaII (OLIG2) protein was cloned downstream of the rat Fabp1 promoter. The polyA sequence was from the SV40 large T antigen. Depending on the founder line anywhere from six to 31 copies of the transgene were incorporated into the genome. (J:55331)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:68515 Gokmen-Polar Y, et al., Elevated protein kinase C betaII is an early promotive event in colon carcinogenesis. Cancer Res. 2001 Feb 15;61(4):1375-81
• All: 2 reference(s)