Tg(Fabp1-OLIG2)54Flds
Transgene Detail

Summary

• Symbol: Tg(Fabp1-OLIG2)54Flds
• Name: transgene insertion 54, Alan P Fields
• MGI ID: MGI:3531327
• Synonyms: line 54, PKC BetaII
• Transgene: Tg(Fabp1-OLIG2)54Flds Location: unknown
• Alliance: Tg(Fabp1-OLIG2)54Flds page

Transgene origin

• Strain of Origin: (C57BL/6J x C3H/HeJ)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Fabp1-OLIG2)54Flds expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  OLIG2 (10215)

  Olig2

  (MGI:1355331)

• Mutation details: A cDNA fragment encoding a full length human PKC BetaII (OLIG2) protein was cloned downstream of the rat Fabp1 promoter. The polyA sequence was from the SV40 large T antigen. Six copies of the transgene were incorporated into the genome. (J:55331)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:55331 Murray NR, et al., Overexpression of protein kinase C betaII induces colonic hyperproliferation and increased sensitivity to colon carcinogenesis. J Cell Biol. 1999 May 17;145(4):699-711
• All: 3 reference(s)