Micu2^{Gt(OST409343)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Micu2^{Gt(OST409343)Lex}
• Name: mitochondrial calcium uptake 2; gene trap OST409343, Lexicon Genetics
• MGI ID: MGI:3531108
• Synonyms: Efha1^{Gt(IRESBetageo)657Lex}, Micu2^-
• Gene: Micu2 Location: Chr14:58153718-58236716 bp, - strand Genetic Position: Chr14, 30.51 cM, cytoband C2
• Alliance: Micu2^{Gt(OST409343)Lex} page

Mutation origin

• Mutant Cell Line: OST409343
• Germline Transmission: Earliest citation of germline transmission: J:94338
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap vector inserted between exons 6 and 7 of the gene. Immunoblotting revealed significantly reduced protein levels in the left ventricle, aorta, and liver tissues from homozygous mutant mice. (J:249367)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST409343	CG650807 ; (MGI Seq Detail)	3' RACE	Chr14:58161428-58170186 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  2 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Micu2 Mutation: 23 strains or lines available

References

• Original: J:94338 NIH Mouse Knockout Inventory, Information obtained from the NIH Mouse Knockout Inventory. MGI Direct Data Submission. 2004
• All: 4 reference(s)