Olfm1^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Olfm1^tm1Lex
• Name: olfactomedin 1; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3528924
• Gene: Olfm1 Location: Chr2:28083105-28120748 bp, + strand Genetic Position: Chr2, 19.38 cM
• Alliance: Olfm1^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:118333
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutations: Insertion, Intragenic deletion
• Exon Y was replaced with a frt-flanked neo selection cassette and exon M2 was flanked by loxP sites. (J:118333)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Olfm1 Mutation: 23 strains or lines available

References

• Original: J:118333 Cheng A, et al., Pancortin-2 interacts with WAVE1 and Bcl-xL in a mitochondria-associated protein complex that mediates ischemic neuronal death. J Neurosci. 2007 Feb 14;27(7):1519-28
• All: 2 reference(s)