Tg(Pim1-E2F2)33Rebr
Transgene Detail
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Symbol: |
Tg(Pim1-E2F2)33Rebr |
Name: |
transgene insertion 33, Rene Bernards |
MGI ID: |
MGI:3527139 |
Synonyms: |
Eu-pp-E2F2, TEF2-33 |
Transgene: |
Tg(Pim1-E2F2)33Rebr Location: unknown
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Alliance: |
Tg(Pim1-E2F2)33Rebr page
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Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Pim1-E2F2)33Rebr expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
E2F1 (1869) |
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Tg(Pim1-E2F2)33Rebr expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Pim1 (MGI:97584) |
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Mutation details: A human E2F2 cDNA was cloned downstream of a murine Pim1 promoter in which a duplicated immunoglobulin heavy chain enhancer sequence was inserted. The polyA sequence was contributed by the Molony murine leukemia virus.
(J:88864)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:88864 Scheijen B, et al., High incidence of thymic epithelial tumors in E2F2 transgenic mice. J Biol Chem. 2004 Mar 12;279(11):10476-83 |
All: |
1 reference(s) |
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