Tagln^tm1Liw
Targeted Allele Detail

Summary

• Symbol: Tagln^tm1Liw
• Name: transgelin; targeted mutation 1, Li Li
• MGI ID: MGI:3526077
• Synonyms: SM22^TMlili
• Gene: Tagln Location: Chr9:45840926-45847356 bp, - strand Genetic Position: Chr9, 25.36 cM
• Alliance: Tagln^tm1Liw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160843
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Intron 1 through the translation initiation site in exon 2 was replaced with a lacZ and neo cassette. The absence of protein expression was confirmed by western blot analysis on aorta and bladder extracts. (J:160843)

Expression

In Mice Carrying this Mutation:

64 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tagln Mutation: 26 strains or lines available

References

• Original: J:160843 Yang M, et al., Sm22alpha transcription occurs at the early onset of the cardiovascular system and the intron 1 is dispensable for its transcription in smooth muscle cells during mouse development. Int J Physiol Pathophysiol Pharmacol. 2010 Jan 1;2(1):12-19
• All: 6 reference(s)