Tg(MMTV-HPV16E6E7)274Gnk
Transgene Detail

Summary

• Symbol: Tg(MMTV-HPV16E6E7)274Gnk
• Name: transgene insertion 274, Gen Kondoh
• MGI ID: MGI:3521864
• Synonyms: HPV16 E6-E7, line 274
• Transgene: Tg(MMTV-HPV16E6E7)274Gnk Location: unknown
• Alliance: Tg(MMTV-HPV16E6E7)274Gnk page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene contains the MMTV LTR (mouse mammary tumor virus long terminal repeat) fused to the HPV16 E6 and E7 orf sequences. The polyA tail is from SV40. Mice possessed 4-5 head to tail copies of the transgene. The transgene followed a Mendalian pattern of inheritance. (J:93826)

Tumor Data

List all tumor models in MMHCdb carrying Tg(MMTV-HPV16E6E7)274Gnk

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:93826 Kondoh G, et al., Very high incidence of germ cell tumorigenesis (seminomagenesis) in human papillomavirus type 16 transgenic mice. J Virol. 1991 Jun;65(6):3335-9
• All: 3 reference(s)