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Tg(rtetR-tetO-cre)40Mhz
Transgene Detail
Summary
Symbol: Tg(rtetR-tetO-cre)40Mhz
Name: transgene insertion 40, Martin Holzenberger
MGI ID: MGI:3513452
Synonyms: Meu40-Cre, MeuCre40, MeuCre40MH, meu-cre line 40
Transgene: Tg(rtetR-tetO-cre)40Mhz  Location: unknown  
Alliance: Tg(rtetR-tetO-cre)40Mhz page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Tg(rtetR-tetO-cre)40Mhz expression driven by 1 gene
 
Mutation detailsThis transgene uses the same construct as in Tg(rtetR-TetO-cre)1Mhz, however, it displayed a mosaic pattern early embryonic, ubiquitous (Meu) Cre expression that was not dependent on nor affected by doxycycline treatment. This line displayed a high level of partial Cre-lox recombination in all tissues examined. (J:94551)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: tetO (bacteria)
Summary of all recombinase alleles driven by tetO.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
MeuCre44, MeuCre17, MeuCre48 are the lines represented by this transgene. See also J:69328.
References
Original:  J:94551 Leneuve P, et al., Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles. Nucleic Acids Res. 2003 Mar 1;31(5):e21
All:  34 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory