Scarb1^Chohd1
Chemically induced Allele Detail

Summary

• Symbol: Scarb1^Chohd1
• Name: scavenger receptor class B, member 1; dominant hypercholesterolemia 1
• MGI ID: MGI:3513434
• Synonyms: CHO004, CHOHD1
• Gene: Scarb1 Location: Chr5:125354151-125418158 bp, - strand Genetic Position: Chr5, 64.11 cM
• Alliance: Scarb1^Chohd1 page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation results in the replacement of glycine by valine at amino acid position 319 of the protein (G319V). (J:86685)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Scarb1 Mutation: 52 strains or lines available

References

• Original: J:94145 Mohr M, et al., Hypercholesterolemia in ENU-induced mouse mutants. J Lipid Res. 2004 Nov;45(11):2132-7
• All: 2 reference(s)