repro14
Chemically induced Allele Detail

Summary

• Symbol: repro14
• Name: reproductive mutant 14, JAX Reproductive Mutagenesis Program
• MGI ID: MGI:3512909
• Synonyms: G1-449-31
• Gene: repro14 Location: Chr5:108762509-114021986 bp Genetic Position: Chr5, Syntenic
• Alliance: repro14 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• This phenotypic mutant was identified in an ENU mutagenesis screen.
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any repro14 Mutation: 0 strains or lines available

Notes

Males and females are infertile: very low testis weight, no epididymal sperm are recovered; in females, no oocytes are recovered. Histological analysis shows arrest of spermatogenesis predominantly at pachytene stage of meiotic prophase or meiotic division stage, some germ cells appear apoptotic. Ovaries are tiny with no growing oocytes or follicles.

References

• Original: J:92463 JAX Reproductive Mutagenesis Program, Heritable mouse mutants from The Jackson Laboratory Reproductive Genomics Mutagenesis Program. MGI Direct Data Submission. 2004-7
• All: 1 reference(s)