Pnmt^tm1(cre)Sne
Targeted Allele Detail

Summary

• Symbol: Pnmt^tm1(cre)Sne
• Name: phenylethanolamine-N-methyltransferase; targeted mutation 1, Steven N Ebert
• MGI ID: MGI:3510456
• Synonyms: Pnmt^cre
• Gene: Pnmt Location: Chr11:98277449-98279006 bp, + strand Genetic Position: Chr11, 61.75 cM, cytoband D
• Alliance: Pnmt^tm1(cre)Sne page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:93831
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Pnmt^tm1(cre)Sne expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pnmt (MGI:97724)

• Mutation details: Cre recombinase and an FRT flanked neomycin resistance gene were inserted into exon 1, creating an in-frame fusion gene. (J:93831)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pnmt (mouse) Summary of all recombinase alleles driven by Pnmt. Alliance mouse Pnmt gene page

Expression

In Mice Carrying this Mutation:

16 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pnmt Mutation: 12 strains or lines available

References

• Original: J:93831 Ebert SN, et al., Targeted insertion of the Cre-recombinase gene at the phenylethanolamine n-methyltransferase locus: A new model for studying the developmental distribution of adrenergic cells. Dev Dyn. 2004 Dec;231(4):849-58
• All: 15 reference(s)