Tg(tetL)1Bjd
Transgene Detail

Summary

• Symbol: Tg(tetL)1Bjd
• Name: transgene insertion 1, Hermann Bujard
• MGI ID: MGI:3056776
• Synonyms: Tg(tetL)1Uh
• Transgene: Tg(tetL)1Bjd Location: unknown
• Alliance: Tg(tetL)1Bjd page

Transgene origin

• Strain of Origin: NMRI

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgene carries the luciferase gene coupled to a tetracycline-responsive promoter element (TRE). (J:93000)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

Transgenic mice are viable, fertile, and do not display an overt phenotype.

In conjunction with a second transgene expressing the tetracycline-controlled activator proteins tTA or rtTA coupled to a tissue-specific promoter (examples include: Tg(Camk2a-tTA)1Mmay, Tg(Myh6-tTA)6Smbf, and Tg(Nes-rtTA)306Rvs), transgenic mice express luciferase in the appropiate tissue in a tetracycline-inducible fashion.

References

• Original: J:93000 Kistner A, et al., Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proc Natl Acad Sci U S A. 1996 Oct 1;93(20):10933-8
• All: 4 reference(s)