Tg(tetNZL)2Bjd
Transgene Detail

Summary

• Symbol: Tg(tetNZL)2Bjd
• Name: transgene insertion 2, Hermann Bujard
• MGI ID: MGI:3056772
• Synonyms: Tg(tetNZL)2Uh
• Transgene: Tg(tetNZL)2Bjd Location: unknown
• Alliance: Tg(tetNZL)2Bjd page

Transgene origin

• Strain of Origin: NMRI

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: In this transgene both the lacZ gene with a nuclear localization signal (NZ) and the luciferase gene (L) are driven by a bidirectional, tetracycline-responsive promoter element (TRE). (J:93001)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

In conjunction with a second transgene expressing the tetracycline-controlled activator proteins tTA or rtTA coupled to a tissue-specific promoter (examples include: Tg(Camk2a-tTA)1Mmay, Tg(Myh6-tTA)6Smbf, and Tg(Nes-rtTA)306Rvs), transgenic mice express lacZ and luciferase in the appropiate tissue in a tetracycline-inducible fashion.

References

• Original: J:93001 Baron U, et al., Co-regulation of two gene activities by tetracycline via a bidirectional promoter. Nucleic Acids Res. 1995 Sep 11;23(17):3605-6
• All: 7 reference(s)