Tomm34^tm1Kate
Targeted Allele Detail

Summary

• Symbol: Tomm34^tm1Kate
• Name: translocase of outer mitochondrial membrane 34; targeted mutation 1, Kazutoyo Terada
• MGI ID: MGI:3055553
• Synonyms: Tom34^-
• Gene: Tomm34 Location: Chr2:163895460-163913089 bp, - strand Genetic Position: Chr2, 84.6 cM, cytoband H3
• Alliance: Tomm34^tm1Kate page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:92492
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neomycin resistance gene was inserted between exons 1a and 1b. Northern blot analysis showed complete absence of mRNA in mutant testes. Western blot showed neither isoform was present in mutant testes. (J:92492)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tomm34 Mutation: 19 strains or lines available

References

• Original: J:92492 Terada K, et al., Expression of Tom34 splicing isoforms in mouse testis and knockout of Tom34 in mice. J Biochem. 2003 May;133(5):625-31
• All: 1 reference(s)