Ods^tm1Ceb
Targeted Allele Detail

Summary

• Symbol: Ods^tm1Ceb
• Name: ocular degeneration with sex reversal; targeted mutation 1, Colin E Bishop
• MGI ID: MGI:3052442
• Synonyms: Delta11.133
• Gene: Ods Location: unknown Genetic Position: Chr11, Syntenic
• Alliance: Ods^tm1Ceb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:91429
• Parent Cell Line: AB2.1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted
• Mutations: Insertion, Intragenic deletion
• Mutation details: Homologous recombination was used to create a 133 kb deletion containing a single copy of HPRT1 with a loxP site in the middle, as well as agouti and tyrosinase minigenes. Southern blot confirmed recombination. This mutation is slightly smaller than the original Ods^{Tg(Tyr)1220Ove} mutation and uses the endogenous tyrosinase promoter rather than the Dct promoter found in the original mutation. (J:91429)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ods Mutation: 0 strains or lines available

References

• Original: J:91429 Qin Y, et al., Long-range activation of Sox9 in Odd Sex (Ods) mice. Hum Mol Genet. 2004 Jun 15;13(12):1213-8
• All: 1 reference(s)