Tg(CAG-DT)3Osb
Transgene Detail

Summary

• Symbol: Tg(CAG-DT)3Osb
• Name: transgene insertion 3, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:3046672
• Synonyms: REP-DT, Tg(ACTB-DT)3Osb, Tg(CAG-[floxed neo]-DT)03Osb
• Transgene: Tg(CAG-DT)3Osb Location: unknown
• Alliance: Tg(CAG-DT)3Osb page

Transgene origin

• Strain of Origin: (C57BL x DBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene consists of the chicken beta-actin promoter, a floxed neo cassette and the diphtheria toxin A chain. Cre mediated recombination removes the neo cassette and allows expression of the diphtheria toxin A chain. (J:91302)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:91302 Matsumura H, et al., Lineage-specific cell disruption in living mice by Cre-mediated expression of diphtheria toxin A chain. Biochem Biophys Res Commun. 2004 Aug 20;321(2):275-9
• All: 4 reference(s)