Tg(B2m-lacZ)2Cba
Transgene Detail

Summary

• Symbol: Tg(B2m-lacZ)2Cba
• Name: transgene insertion 2, Charles Babinet
• MGI ID: MGI:3044122
• Synonyms: beta-2 microgl. prom./beta-galact., beta2m LacZ, beta2nZ 2, beta2nZ2
• Transgene: Tg(B2m-lacZ)2Cba Location: unknown
• Alliance: Tg(B2m-lacZ)2Cba page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL/J)F2

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgene comprises the 5' regulatory region and the first four codons of the beta-2 microglobulin gene followed, in-frame, by the beta-galactosidase (lacZ) gene and nuclear localization sequences and, in the same transcriptional orientation, the Herpes simplex virus thymidine kinase/neomycin resistance fusion gene. Beta-galactosidase is expressed under control of the beta-2 microglobulin promoter. (J:79264)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:79264 Cohen-Tannoudji M, et al., Unexpected position-dependent expression of H-2 and beta 2-microglobulin/lacZ transgenes. Mol Reprod Dev. 1992 Oct;33(2):149-59
• All: 1 reference(s)