Glra3^tm1Umu
Targeted Allele Detail

Summary

• Symbol: Glra3^tm1Umu
• Name: glycine receptor, alpha 3 subunit; targeted mutation 1, Ulrike Muller
• MGI ID: MGI:3043775
• Gene: Glra3 Location: Chr8:56393495-56583105 bp, + strand Genetic Position: Chr8, 29.69 cM
• Alliance: Glra3^tm1Umu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:89981
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 7 and a neo cassette both flanked by loxP sites were inserted via homologous recombination. (J:89981)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Glra3 Mutation: 38 strains or lines available

References

• Original: J:89981 Harvey RJ, et al., GlyR alpha3: an essential target for spinal PGE2-mediated inflammatory pain sensitization. Science. 2004 May 7;304(5672):884-7
• All: 1 reference(s)