Ckbtm1Bew
Targeted Allele Detail
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Symbol: |
Ckbtm1Bew |
Name: |
creatine kinase, brain; targeted mutation 1, Be Wieringa |
MGI ID: |
MGI:3042843 |
Synonyms: |
B-CK- |
Gene: |
Ckb Location: Chr12:111635795-111638772 bp, - strand Genetic Position: Chr12, 61.09 cM
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Alliance: |
Ckbtm1Bew page
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Germline Transmission: |
Earliest citation of germline transmission:
J:89399
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exon 2 including the translation start site was deleted and replaced with a neo-cassette via homologous recombination. Absence of RNA expression and enzyme activity were confirmed by northern blot analysis and activity assays.
(J:89399)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ckb Mutation: |
27 strains or lines available
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Original: |
J:89399 Jost CR, et al., Creatine kinase B-driven energy transfer in the brain is important for habituation and spatial learning behaviour, mossy fibre field size and determination of seizure susceptibility. Eur J Neurosci. 2002 May;15(10):1692-706 |
All: |
7 reference(s) |
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