Tg(Bglap2-cre)2Kry
Transgene Detail

Summary

• Symbol: Tg(Bglap2-cre)2Kry
• Name: transgene insertion 2, Gerard Karsenty
• MGI ID: MGI:3041872
• Synonyms: artificial OG2-Cre
• Transgene: Tg(Bglap2-cre)2Kry Location: unknown
• Alliance: Tg(Bglap2-cre)2Kry page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Bglap2-cre)2Kry expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Bglap2

• Mutation details: An engineered promoter region was derived from the Bglap2 proximal region, consisting of 6 copies of two osteoblast-specific cis-acting elements, OSE2 and OSE1. This promoter region was adjoined to sequence encoding cre recombinase, which was expressed in both bone and cartilage tissue. (J:77071)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Bglap2 (species not specified) Summary of all recombinase alleles driven by Bglap2. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:77071 Dacquin R, et al., Mouse alpha1(I)-collagen promoter is the best known promoter to drive efficient Cre recombinase expression in osteoblast. Dev Dyn. 2002 Jun;224(2):245-51
• All: 1 reference(s)