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Tg(Pbsn-Tag)12T10Rjm
Transgene Detail
Summary
Symbol: Tg(Pbsn-Tag)12T10Rjm
Name: transgene insertion 12T10, Robert J Matusik
MGI ID: MGI:3040284
Synonyms: 12T-10, Lady, Lady-12-T10, LBP-Tag, Tg(Tag)12T10Rjm
Transgene: Tg(Pbsn-Tag)12T10Rjm  Location: unknown  
Alliance: Tg(Pbsn-Tag)12T10Rjm page
Transgene
origin
Strain of Origin:  CD-1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe transgene includes the SV40 large T antigen (Tag) gene, containing a deletion in the early region that eliminates expression of small T antigen, driven by the rat probasin promoter fragment extending from -11500 to +28 bp ("large probasin promoter"). (J:48623)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Tumor Data
List all tumor models in MMHCdb carrying Tg(Pbsn-Tag)12T10Rjm
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
Transgenic lines were established and maintained in the CD1 mouse strain.
References
Original:  J:48623 Kasper S, et al., Development, progression, and androgen-dependence of prostate tumors in probasin-large T antigen transgenic mice: a model for prostate cancer [corrected and republished article originally printed in Lab Invest 1998 Mar;78(3):319-33]. Lab Invest. 1998 Jun;78(6):i-xv
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory