Tg(MSV)125Pgr
Transgene Detail

Summary

• Symbol: Tg(MSV)125Pgr
• Name: transgene insertion 125, Peter Gruss
• MGI ID: MGI:3040253
• Transgene: Tg(MSV)125Pgr Location: unknown
• Alliance: Tg(MSV)125Pgr page

Transgene origin

• Strain of Origin: either: NMRI or (NMRI x B6D2F1)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene contains the SV40 early gene promoter, the Moloney murine sarcoma virus enhancer, and the wild-type allele of the SV40 large T antigen (TAg) gene. (J:90321)

Tumor Data

List all tumor models in MMHCdb carrying Tg(MSV)125Pgr

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Tumors in the pancreas and pineal gland were observed.

References

• Original: J:90321 Theuring F, et al., Tumorigenesis and eye abnormalities in transgenic mice expressing MSV-SV40 large T-antigen. Oncogene. 1990 Feb;5(2):225-32
• All: 5 reference(s)