Tg(IgTp-T)3Yik
Transgene Detail

Summary

• Symbol: Tg(IgTp-T)3Yik
• Name: transgene insertion 3, Yoji Ikawa
• MGI ID: MGI:3039904
• Synonyms: Tg/Tp-T, Tg/Tp-TNo
• Transgene: Tg(IgTp-T)3Yik Location: unknown
• Alliance: Tg(IgTp-T)3Yik page

Transgene origin

• Strain of Origin: (C57BL/6CrSlc x CD-1)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene contains the simian virus 40 early gene promoter and the wild-type allele of the SV40 large T antigen (TAg) gene. The construct also contains mouse Ig heavy chain enhancer sequences. (J:46455)

Tumor Data

List all tumor models in MMHCdb carrying Tg(IgTp-T)3Yik

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Founder numbers 1, 3, 5, 8, 9, 10, 11, 12, 13, 14, 15 were generated. Lines 3, 8, 9, 10, 11, 12, 13, 14, and 15 were generated, differing in such parameters as copy number, number of integrations, and tumor frequency and tissue.

References

• Original: J:46455 Suda Y, et al., Driven by the same Ig enhancer and SV40 T promoter ras induced lung adenomatous tumors, myc induced pre-B cell lymphomas and SV40 large T gene a variety of tumors in transgenic mice. EMBO J. 1987 Dec 20;6(13):4055-65
• All: 1 reference(s)