Tg(BK5-IGF1)2Jdg
Transgene Detail

Summary

• Symbol: Tg(BK5-IGF1)2Jdg
• Name: transgene insertion 2, John DiGiovanni
• MGI ID: MGI:3039667
• Transgene: Tg(BK5-IGF1)2Jdg Location: unknown
• Alliance: Tg(BK5-IGF1)2Jdg page

Transgene origin

• Strain of Origin: (FVB x ICR)F1

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Human insulin-like growth factor 1 cDNA driven by the bovine keratin 5 promoter. (J:62011)

Tumor Data

List all tumor models in MMHCdb carrying Tg(BK5-IGF1)2Jdg

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:62011 DiGiovanni J, et al., Constitutive expression of insulin-like growth factor-1 in epidermal basal cells of transgenic mice leads to spontaneous tumor promotion. Cancer Res. 2000 Mar 15;60(6):1561-70
• All: 8 reference(s)