Tg(Arr2/Pbsn-FGFR1K656E)1Wmck
Transgene Detail
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Symbol: |
Tg(Arr2/Pbsn-FGFR1K656E)1Wmck |
Name: |
transgene insertion 1, Wallace L McKeenan |
MGI ID: |
MGI:3039371 |
Synonyms: |
ARR2PBi-caFGFR1, Tg(Arr2/Pbsn-FGFR1K656E)W |
Transgene: |
Tg(Arr2/Pbsn-FGFR1K656E)1Wmck Location: unknown
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Alliance: |
Tg(Arr2/Pbsn-FGFR1K656E)1Wmck page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Arr2/Pbsn-FGFR1K656E)1Wmck expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
FGFR1 (2260) |
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Mutation details: The human two immunoglobulin-loop isoform of FGFR1 bearing the K656E mutation and an artificial FLAG epitope was inserted downstream of the ARR2PB composite promoter that consists of a minimal probasin promoter that was modified to contain two androgen response elements. RT-PCR analysis showed that transgene expression is limited to the prostate gland.
(J:87067)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:87067 Jin C, et al., Cooperation between ectopic FGFR1 and depression of FGFR2 in induction of prostatic intraepithelial neoplasia in the mouse prostate. Cancer Res. 2003 Dec 15;63(24):8784-90 |
All: |
1 reference(s) |
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