Tg(MMTV-Fgf3)NW1Mul
Transgene Detail

Summary

• Symbol: Tg(MMTV-Fgf3)NW1Mul
• Name: transgene insertion NW1, William J Muller
• MGI ID: MGI:3039045
• Synonyms: TG.NW, TG.NW-F
• Transgene: Tg(MMTV-Fgf3)NW1Mul Location: unknown
• Alliance: Tg(MMTV-Fgf3)NW1Mul page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(MMTV-Fgf3)NW1Mul expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Fgf3 (MGI:95517)

• Mutation details: This transgene contains the full mouse mammary tumor virus promoter and the mouse fibroblast growth factor 3 gene (Fgf3, formerly int-2). The transgene construct also contained SV40 poly A. (J:71557)

Tumor Data

List all tumor models in MMHCdb carrying Tg(MMTV-Fgf3)NW1Mul

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

The founder mouse was sterile. Transgene expression was detected at high levels in seminal vesicles, detected at lower levels in the prostate and salivary gland, and not detected in the vas deferens.

References

• Original: J:71557 Muller WJ, et al., The int-2 gene product acts as an epithelial growth factor in transgenic mice. EMBO J. 1990 Mar;9(3):907-13
• All: 1 reference(s)