Foxo4^tm1Kca
Targeted Allele Detail

Summary

• Symbol: Foxo4^tm1Kca
• Name: forkhead box O4; targeted mutation 1, Karen C Arden
• MGI ID: MGI:3038982
• Synonyms: Foxo4^-
• Gene: Foxo4 Location: ChrX:100298134-100304479 bp, + strand Genetic Position: ChrX, 43.89 cM
• Alliance: Foxo4^tm1Kca page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:88638
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaced exon 1 via homologous recombination. Northern blot analysis confirmed the absence of RNA expression in skeletal muscle from homozygotes (J:88638)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxo4 Mutation: 13 strains or lines available

References

• Original: J:88638 Hosaka T, et al., Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification. Proc Natl Acad Sci U S A. 2004 Apr 2;101(9):2975-80
• All: 1 reference(s)