Idd14^NOD/ShiLt
QTL Variant Detail

Summary

• QTL variant: Idd14^NOD/ShiLt
• Name: insulin dependent diabetes susceptibility 14; NOD/ShiLt
• MGI ID: MGI:3036817
• QTL: Idd14 Location: unknown Genetic Position: Chr13, cM position of peak correlated region/allele: 20.16 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: NOD/ShiLt

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers susceptibility to insulin dependent diabetes compared to NON/Lt. (J:28947)
• Inheritance: Not Specified

Notes

Homozygosity for NOD/Lt-derived alleles confers type 1 diabetes susceptibility.

References

• Original: J:28947 Mcaleer MA, et al., Crosses of NOD mice with the related NON strain: A polygenic model for IDDM. Diabetes. 1995 OCT;44(10):1186-1195
• All: 1 reference(s)