Kit^W-2Bao
Chemically induced Allele Detail

Summary

• Symbol: Kit^W-2Bao
• Name: KIT proto-oncogene receptor tyrosine kinase; dominant spotting 2 Baojin
• MGI ID: MGI:3033409
• Gene: Kit Location: Chr5:75735647-75817382 bp, + strand Genetic Position: Chr5, 39.55 cM
• Alliance: Kit^W-2Bao page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This allele is defined by its location between D5Mit356 and D5Mit308 and classic "black-eyed, white coat" appearance of the homozygote. The mutation was identified as a G to T transversion at nucleotide position 1229, causing a V to F change at amino acid 410.
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kit Mutation: 179 strains or lines available

References

• Original: J:88137 Wu B, et al., Four kinds of ENU-induced white spot mice and Chromosome locations of the mutant genes. Chinese Science Bulletin. 2003;48(24):2658-2664
• All: 2 reference(s)