About   Help   FAQ
Targeted Allele Detail
Symbol: Slc25a13tm1Lct
Name: solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13; targeted mutation 1, Lap-Chee Tsui
MGI ID: MGI:3028639
Synonyms: Ctrn -/-
Gene: Slc25a13  Location: Chr6:6041218-6217173 bp, - strand  Genetic Position: Chr6, 2.3 cM, cytoband A1
Alliance: Slc25a13tm1Lct page
Germline Transmission:  Earliest citation of germline transmission: J:87578
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA 347 bp region containing exon 10 was replaced with a neomycin resistance gene inserted in opposite orientation. Absence of mRNA transcript was confirmed by Northern blot and absence of protein product by Western blot analysis. (J:87578)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Slc25a13 Mutation:  170 strains or lines available
Original:  J:87578 Sinasac DS, et al., Slc25a13-knockout mice harbor metabolic deficits but fail to display hallmarks of adult-onset type II citrullinemia. Mol Cell Biol. 2004 Jan;24(2):527-36
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
MGI 6.22
The Jackson Laboratory