mdac
Spontaneous Allele Detail

Summary

• Symbol: mdac
• Name: modifier of Dac; recessive modifier of Dac
• MGI ID: MGI:3027244
• Gene: Mdac Location: Chr13:56275796-65109572 bp Genetic Position: Chr13, Syntenic
• Alliance: mdac page

Mutation origin

• Strain of Origin: multiple strains

Mutation description

• Allele Type: Spontaneous
• Inheritance: Recessive

Disease models

Expression

In Mice Carrying this Mutation:

32 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mdac Mutation: 0 strains or lines available

Notes

Presence of this allele in the homozygous state is necessary for expression of dactylaplasia in Dac/+ mice. It is homozygous in strains SM, BALB/c, LG, and 129/J. The dominant allele occurs in strains C57BL/6, DBA/2, CBA/J, AKR, and SWR. There is no visible effect on the feet of mdac/mdac in the absence of Dac alleles (J:6607).

References

• Original: J:6607 Chai CK, Dactylaplasia in mice a two-locus model for development anomalies. J Hered. 1981 Jul-Aug;72(4):234-7
• All: 5 reference(s)