Egr1^tm1Lch
Targeted Allele Detail

Summary

• Symbol: Egr1^tm1Lch
• Name: early growth response 1; targeted mutation 1, Serge Laroche
• MGI ID: MGI:2683282
• Gene: Egr1 Location: Chr18:34994260-34998009 bp, + strand Genetic Position: Chr18, 18.76 cM, cytoband C/D
• Alliance: Egr1^tm1Lch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:86638
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A lacZ-neomycin cassette was inserted between the promoter and coding sequence. There was also a frame shift at the beginning of the DNA binding domain. In situ hybridization studies confirmed the absence of product while LTP-inducible expression of LacZ was demonstrated. (J:86638)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Egr1 Mutation: 19 strains or lines available

References

• Original: J:86638 Bozon B, et al., A requirement for the immediate early gene zif268 in reconsolidation of recognition memory after retrieval. Neuron. 2003 Nov 13;40(4):695-701
• All: 1 reference(s)