S100a11^tm1Wen
Targeted Allele Detail

Summary

• Symbol: S100a11^tm1Wen
• Name: S100 calcium binding protein A11; targeted mutation 1, Wolfgang Engel
• MGI ID: MGI:2681771
• Synonyms: Cal4^-
• Gene: S100a11 Location: Chr3:93427803-93433595 bp, + strand Genetic Position: Chr3, 40.51 cM, cytoband E-F
• Alliance: S100a11^tm1Wen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:86467
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 which include the complete open reading frame were replaced with a PGK-neomycin cassette. Northern blot analysis confirmed the absence of mRNA transcripts. (J:86467)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any S100a11 Mutation: 20 strains or lines available

References

• Original: J:86467 Mannan AU, et al., Calgizarrin like gene (Cal) deficient mice undergo normal spermatogenesis. Mol Reprod Dev. 2003 Dec;66(4):431-8
• All: 1 reference(s)