Slc30a5^tm1Ynak
Targeted Allele Detail

Summary

• Symbol: Slc30a5^tm1Ynak
• Name: solute carrier family 30 (zinc transporter), member 5; targeted mutation 1, Yusuke Nakamura
• MGI ID: MGI:2681466
• Synonyms: Znt5^-
• Gene: Slc30a5 Location: Chr13:100939156-100969935 bp, - strand Genetic Position: Chr13, 53.23 cM, cytoband D1
• Alliance: Slc30a5^tm1Ynak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:86455
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Exon 9 was disrupted by the insertion of a neomycin selection cassette. Transcribed products were reported to be truncated and lacking sequence encoding the cation-efflux domain. (J:86455)

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc30a5 Mutation: 58 strains or lines available

References

• Original: J:86455 Inoue K, et al., Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5. Hum Mol Genet. 2002 Jul 15;11(15):1775-84
• All: 2 reference(s)