Shh^tm1Tmj
Targeted Allele Detail

Summary

• Symbol: Shh^tm1Tmj
• Name: sonic hedgehog; targeted mutation 1, Thomas M Jessell
• MGI ID: MGI:2678342
• Synonyms: Shh^Ires-LacZ, Shh^lacZ, Shh^nLacZ, Shh^tm4Amc
• Gene: Shh Location: Chr5:28661838-28672099 bp, - strand Genetic Position: Chr5, 14.39 cM
• Alliance: Shh^tm1Tmj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:85603
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A cassette containing IRES-lacZ was inserted at the endogenous locus. The expression pattern of lacZ was similar to that of the endogenous gene. (J:85603)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Shh Mutation: 48 strains or lines available

References

• Original: J:85603 Machold R, et al., Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. Neuron. 2003 Sep 11;39(6):937-50
• All: 10 reference(s)