Stk11^tm1Jish
Targeted Allele Detail

Summary

• Symbol: Stk11^tm1Jish
• Name: serine/threonine kinase 11; targeted mutation 1, Kou-ichi Jishage
• MGI ID: MGI:2676471
• Gene: Stk11 Location: Chr10:79951637-79966516 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Stk11^tm1Jish page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:77213
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: Exons 2 through 8 were flanked by floxed neo cassette in intron 1 and a single loxP site in intron 8. (J:77213)

Generation of the Stk11^tm1Jish and Stk11^tm1.1Jish alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stk11 Mutation: 34 strains or lines available

References

• Original: J:77213 Jishage K, et al., Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8903-8
• All: 1 reference(s)